While I'm not a big fan of vitamin supplementation in isolated forms because in isolating vitamins from their natural sources, the synergistic role other compounds and nutrients in the natural sources have in making the vitamin useful is not always accounted for. E is a perfect example where it was isolated from natural sources like almonds, avocados and sunflower seeds, etc. then it was found E wasn't usable without the dietary fat (lipids) found with it's natural sources.
I do think however, many natural sources for vitamins and minerals are not as replete with them as they once were. In many cases natural sources are fairly deficient in the vitamins and minerals they should contain. Studies have shown that since around the 1930s top soils are no longer rich in the nutrients and minerals necessary to properly fortify food sources, as a result they've become deficient, we eat them (or not in many cases) relying on their purported nutritional value and in some cases we become deficient.
I think it's a good idea to find out what your particular nutritional needs are (first) then supplement with fortified, natural sources as long as you don't exceed the upper limits.
Our deficient diets, stress, cooking vitamins and nutrients out of food, etc. make it smart if not necessary to supplement our vitamin uptake nowadays.
